Dr. Kara N. Maxwell, assistant professor of medicine at the Perelman School of Medicine at the University of Pennsylvania, is the lead author of the study published December 2021 in the European Urology, “Inherited TP53 Variants and Risk of Prostate Cancer.” The team of American researchers concluded that men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer. Dr. Colin Pritchard, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, stated, “Prostate cancer is a disease of older men… But now, with screening, many men with Li-Fraumeni syndrome are living into their 40s, 50s, 60s and 70s, when the risk of prostate cancer is higher.” K.N. Maxwell, H.H. Cheng, J. Powers et al., Inherited TP53 Variants and Risk of Prostate Cancer, Eur Urol (2021), https://doi.org/10.1016/j.eururo.2021.10.036