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Is there treatment for LFS?

Li-Fraumeni Syndrome predisposes certain people to multiple different types of cancer and often multiple cancers and multiple tumors over their lifetime. There currently is no way to “fix” the defective p53 gene mutation. LFS cancers are treated similarly to those in patients without LFS, with some exceptions. In general, it is believed that radiation treatment should be avoided if possible, as LFS-affected individuals appear to be at higher risk for radiation induced cancers. Radiation from CT scans and x-rays should be limited for similar reasons. There are many cases where scans or x-rays can not be avoided, and in those cases, it is best to make both the attending doctors and the technicians aware of the potential for radiation sensitivity to reduce the chance of unnecessary or additional exposure.

LFS is a complex syndrome with wide reaching implications for individuals and their families. For this reason, we suggest that patients with LFS or suspected LFS consult with a provider or institution that has experience caring for patients with Li-Fraumeni Syndrome. In doing so, it is our hope that patients will be provided the highest level of medical care, genetic counseling, and social support services available.

LFS Association

We are families, like you who have been devastated by the effects of Li-Fraumeni Syndrome, a hereditary cancer predisposition syndrome. Our hopes are to educate, raise awareness and find better screening programs and treatments for LFS.


Medical Resources

We've compiled a list of doctors available to
answer your questions, LFS support and
treatment. They specialize in many different
areas, which have been listed with their


LFS News

WETB’s Gayle Ong was one of several reporters covering the event and story of LFS and Mo Songs for Kerry.

Read More…

Community Events

Carly Grant – Mohawk Hudson River Marathon 2017
Support Carly and the Li-Fraumeni Syndrome Association as she raises money and trains for the Mohawk Hudson River Marathon on October 8th!


LFS Webinars

Check out our library to watch past LFS
webinars, and to find out about
upcoming webinars!

Learn more...

LFS Awareness Brochure

Myriad Genetics is proud to partner with LFSA to launch the global LFS Education and Awareness Campaign!