The 4th International LFS Association Symposium hosted by The Hospital for Sick Children and in partnership with the LiFE Consortium was held on April 25 through 29, 2018. Thanks to the leadership of Dr. David Malkin of Toronto Sick Children’s Hospital, there were over 50 of the world’s foremost physicians and scientists in the fields of cancer genetics and LFS research who presented at the conference. Over 300 physicians, scientists, specialists, and family members affected by LFS from across the globe participated. Videos featuring all the speaker discussing their latest research, mostly still not yet even published, are now available on our website.