We are families, like you who have been devastated by the effects of Li-Fraumeni Syndrome (LFS), a hereditary genetic cancer predisposition syndrome. Our hopes are to educate, raise awareness, and find better screening programs and treatments for LFS. By forming relationships with and supporting the variety of researchers and medical staff who can help achieve this, we wish to help provide a better understanding of a complex syndrome to those who need it. We welcome communication with all professionals, researchers, scientists, doctors, patients, and families in the hopes that the bridges formed by these communities will lead to an end of the devastating effects of Li-Fraumeni and other Li-Fraumeni-like syndromes.

In November 2010, with the support of the United States’ National Institute of Health (NIH) and the world’s medical leaders of the Li-Fraumeni Syndrome, we all met in Washington D.C. at the first Li-Fraumeni Syndrome Conference. One month later, in December 2010, we officially formed the LFS Association and selected our inaugural Board of Directors.

Frederick Li & Joseph Fraumeni, 1991
(Photo credit: Division of Cancer Epidemiology and Genetics, National Cancer Institute.)

Learn More About Drs. Frederick Li and Joseph Fraumeni

At the 4th LFSA International Symposium in Toronto, LFSA presented our inaugural Global Pioneer Award for the groundbreaking work of both Drs. Fred Li and Joseph Fraumeni during a reception at the Hockey Hall of Fame. Watch Dr. Fraumeni’s remarks regarding the early collaborative efforts in their recognition of what was later referred to as Li-Fraumeni syndrome. Note the warmth and respect he offers for not only the relationships developed early in his career, but the admiration he has towards those who continue the pursuit to improve the lives of those with LFS.

Uncovering the Causes of Cancer in the Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute: Watch DCEG Director Dr. Stephen Chanock discuss the visionary work of Drs. Joseph Fraumeni, Robert Hoover, and Margaret Tucker as the first generation of researchers at NCI to focus on the etiology of cancer and the environmental, lifestyle, and genetic influences on cancer. Also featured is Dr. Maria Achatz, the principal investigator of the LFS study at NCI, discussing the early discovery of LFS and the significance of LFS research in  carcinogenesis, in general. (October 2017)

The Li-Fraumeni Exploration (LiFE) Research Consortium is composed of dedicated physicians and scientists from around the world. They share a goal of helping to improve the lives of those living with LFS and are advancing our knowledge of this condition through collaborative research.

Learn More About the Next Generation of LFS Researchers

Dr. Judy Garber

Dr. David Malkin

Dr. Louise Strong

Dr. Joshua Schiffman

Dr. Sharon Savage

Dr Maria Isabel Waddington Achatz, MD

  • Sue Armstrong’s “Brazil’s Cancer Curse” (published September 15, 2015).
  • LFS Association International Chapter Chair – Latin America
  • LFS Association Scientific Advisory Board Member

Dr. Christian Kratz, MD

  • Medizinische Hochschule Hannover
  • LFS Association International Chapter Chair – Germany
  • LFS Association Medical Advisory Board Member

Dr. Kim E. Nichols, MD

Dr. Phuong Mai, MD

  • LFS Association Medical Advisory Board

Dr. Payal Kincha, MD

Dr. Gareth Evans, MD

Dr. Jeffrey Weitzel, MD

It is with heartfelt appreciation that we acknowledge Sabre Digital Marketing for their continued support with our website, which is our first ever communication tool linking our worldwide LFS community together. Without Sabre Digital Marketing, none of this would have been possible – Thank you!