LFS Association’s Insurance Basics for Individuals with LFS (2022)
LFS Association’s “quick” LFS Fact Sheet for Medical Providers (2021)
LFS Association’s Awareness “quick” Fact Sheet, Genetics Matter (2021)
LFS Association’s Awareness Brochure (2018)
LFS Association’s Quick Reference Resource for Mental Health Providers regarding concerns for LFS patients (2021)
Nature: Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations (2017)
NCI Fact Sheet: Cancer in Children and Adolescents (May 2014)
NCI Patient Education: Pain Control – Support for People with Cancer (May 2014)
NCI Li-Fraumeni Syndrome Study list of publications
NCI Fact Sheet: Cancer Staging (January 2015)
NCI Cancer Topics: Coping with Cancer (December 2015)
Cancer.Net: Li-Fraumeni Syndrome (November 2014)
NCI Patient Education Publications (October 2014)
NCI Fact Sheet: Targeted Cancer Therapies (April 2013)
MD Anderson Cancer Center’s Patient Education handout: Li-Fraumeni Syndrome (April 2014)
NCI Fact Sheet: Genetic Testing for Hereditary Cancer Syndromes (April 2013)
NCBI GeneReview: Li-Fraumeni Syndrome (Schneider, Zelley, Nichols, & Garber, April 2013)
NCI Fact Sheet: Cancer Clinical Trials (February 2013)
The birth of the LiFE Consortium and the roots of the LFS Association – Li-Fraumeni Syndrome: report of clinical research workshop and creation of a research consortium (August 2012)
NCBI Bookshelf: Li-Fraumeni Syndrome (Malkin, April 2011)
The first publications on Li-Fraumeni syndrome, before it was called Li-Fraumeni syndrome, referred to it as “a familial cancer syndrome”:
LFS was first documented in October 1969: “Soft-Tissue Sarcomas, Breast Cancer, and Other Neoplasms – A Familial Syndrome?”
By December 1969, it was no longer a question: “Rhabdomyosarcoma in Children: Epidemiologic Study and Identification of a Familial Cancer Syndrome.”
The familial cancer syndrome was first referred to as Li-Fraumeni syndrome in a 1982 publication by British researchers: “Two families with the Li-Fraumeni cancer family syndrome.”
Cancers reported in LFS families. Click on the cancer type to reach the National Cancer Institute’s patient education library:
Carcinomas (cancers that originate in a tissue that lines the inner or outer surfaces of the body, also known as epithelial cells)
Sarcomas (cancers that arises from transformed cells of mesenchymal origins)
Leukemias (originate from bone marrow) and Lymphomas (originate in the lymphatic tissues)
Skin cancers
