2011: Monograph on Li-Fraumeni Syndrome by David Malkin
Li-Fraumeni syndrome (LFS) is a genetic disorder linked to mutations in the p53 tumor suppressor gene, leading to a wide range of
1988: A cancer family syndrome in twenty-four kindreds by Fred Li
Researchers analyzed families with a pattern of sarcomas, breast cancer, and other cancers occurring in young patients. They found that cancer developed
1987: Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro
Researchers tested cells from people with Li-Fraumeni Syndrome (LFS), a genetic condition that increases cancer risk, to see how they respond
Reginalda
I discovered the syndrome through genetic testing after battling breast cancer and undergoing bilateral mastectomy. Today, I find myself navigating
Shirley
I discovered Li-Fraumeni syndrome one week before quadrant surgery for breast cancer. I found out about the cancer in April
Anna Carolina
I discovered that I have Li-Fraumeni syndrome in 2021. At the time, my mastologist asked me for a genetic
A Kick-Ass Fairy: A Memoir
WHAT DOES IT MEAN TO BE A KICK-ASS FAIRY? Looking for a fairy tale to make into a musical?
Attention Young Adults between 18-29 living in the US of A!
Would you like to participate in a research study at the National Cancer Institute that is developing a mental health resource for young adults
2011: Monograph on Li-Fraumeni Syndrome by David Malkin
Li-Fraumeni syndrome (LFS) is a genetic disorder linked to mutations in the p53 tumor suppressor gene, leading to
1988: A cancer family syndrome in twenty-four kindreds by Fred Li
Researchers analyzed families with a pattern of sarcomas, breast cancer, and other cancers occurring in young patients. They
1987: Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro
Researchers tested cells from people with Li-Fraumeni Syndrome (LFS), a genetic condition that increases cancer risk, to
Hot off the press!!! Genotype–phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry.
In 2017, not only did Dr. Christian Kratz launch our international chapter, LFSA – Germany, but he also founded the German Cancer Predisposition Syndrome
New publication! Cancer surveillance for patients with LFS in Brazil
Dr. Maria Isabel Achatz led a recent publication on the cost-effectiveness of Cancer surveillance for patients with LFS in Brazil using the Toronto Protocol screening
NCI: Making Strides Toward Precision Medicine for Individuals with Li-Fraumeni Syndrome
Read about the advancements in LFS research that our team at the Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, have accomplished in their
Psychological Impact of TP53-Variant-Carrier Newborns and Counselling on Mothers: A Pediatric Surveillance Cohort
This study examined anxiety and depression in mothers of newborns carrying the TP53 p.R337H variant in southern Brazil. Mothers of carriers showed higher anxiety shortly
Li-Fraumeni Syndrome Association Lauds Advancements in Classifying Hereditary Cancer Risks
HOLLISTON, MA -- The Li-Fraumeni Syndrome Association (LFSA), dedicated to furthering research and worldwide awareness of the inherited cancer predisposition disorder, celebrates new findings
Li-Fraumeni syndrome: not a straightforward diagnosis anymore
With advances in genetic testing, researchers and providers have been facing challenges in interpreting the pathogenic variants of TP53. Li-Fraumeni syndrome: not a straightforward diagnosis
