A prospective study of Annual Whole-Body MRI as Part of a Multimodality Screening Program for Individuals with Li-Fraumeni Syndrome
US-based researchers assessed the performance of (non-contrast) annual whole-body MRI as part of a multimodality screening for individuals with Li-Fraumeni syndrome for
Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome
New prospective data from a German study indicate that annual whole-body MRI for LFS surveillance could be shortened and may not
LFSA – Africa! “Rare genetic disorder that helps cancer run in families”
Lakita at the LFSA's Youth Workshop in 2023 LFSA - Africa's Media Relations Specialist Joel Magu has published another article
LFSA Co-Founder Debbie Soprano Honored by Boston Children’s Hospital
The Li-Fraumeni Syndrome Association (LFSA) is proud to announce that Co-Founder and Board Member Debbie Soprano has been recognized
Annual Whole-Body Imaging Contributes to Early Cancer Detection in Patients With Li-Fraumeni Syndrome
Researchers at the Dana-Farber Cancer Institute concluded that annual whole-body MRIs contribute substantially to detection of asymptomatic localized cancers among
Seeking Participants for the INFORM Research Study
Dana-Farber is leading an IRB-approved study that will screen for many of the deadliest cancers with a first-of-its-kind blood
Update on Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome
Published March 2025 by American Association for Cancer Research (AACR) is the updated version of the “Toronto Protocol,” the
Clinical Characteristics and Cancer Histories Among Breast Cancer Patients With Li-Fraumeni Syndrome From a Single Institution
Diagnosing Li-Fraumeni syndrome soon after a patient's first cancer can reduce their overall cancer burden with an improved, personalized plan. Faster identification enables earlier
A prospective study of Annual Whole-Body MRI as Part of a Multimodality Screening Program for Individuals with Li-Fraumeni Syndrome
US-based researchers assessed the performance of (non-contrast) annual whole-body MRI as part of a multimodality screening for individuals
Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome
New prospective data from a German study indicate that annual whole-body MRI for LFS surveillance could be
LFSA – Africa! “Rare genetic disorder that helps cancer run in families”
Lakita at the LFSA's Youth Workshop in 2023 LFSA - Africa's Media Relations Specialist Joel Magu
Whole Body MRI Anxiety
A unique aspect of the LFSA International Symposium is the intersection of LFS families among globally renowned medical and scientific experts. Lisa J. States,
Another survey opportunity: Risk-reducing mastectomy decision making process for adolescents and young adults with Li-Fraumeni Syndrome
Another invitation to participate in a study about the risk-reducing mastectomy decision making process for adolescents and young adults with Li-Fraumeni Syndrome: A team
Jenn Perry on WEEI for Jimmy Fund Telethon
LFSA founder Jenn Perry shares her family's LFS story and what motivates her to advocate for research and advancements to support those impacted by Li-Fraumeni
2011: Monograph on Li-Fraumeni Syndrome by David Malkin
Li-Fraumeni syndrome (LFS) is a genetic disorder linked to mutations in the p53 tumor suppressor gene, leading to a wide range of cancers. While p53
1988: A cancer family syndrome in twenty-four kindreds by Fred Li
Researchers analyzed families with a pattern of sarcomas, breast cancer, and other cancers occurring in young patients. They found that cancer developed in an autosomal
1987: Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro
Researchers tested cells from people with Li-Fraumeni Syndrome (LFS), a genetic condition that increases cancer risk, to see how they respond to DNA-damaging agents
