Ovarian cancers have been documented in LFS patients as early as the 1980s
September is Ovarian Cancer Awareness Month! Although not originally recognized as a common “core” cancer in Li-Fraumeni syndrome (LFS), ovarian cancers were documented (1) as subsequent tumors in patients with Li-Fraumeni syndrome as early as 1988. And though still considered “rare” in LFS, reproductive cancers are highlighted in research. In an August 2026 study by



