Genetic testing is not always a one and done process: the classification of a variant may change over time, technologies improve and better testing may become available; and guidelines and recommendations for testing and management change as we learn new information. This case in “Genetic Testing Challenges in Oncology" highlights some of these issues. The
Through the tremendous generosity of the Lesko and Fleming families, a newly established annual grant program will provide support for two youth personally impacted by Li-Fraumeni syndrome. Honoring the meaningful life and enduring memory of Cody Lesko, the empowerment grants will support adolescents and young adults to offset costs of enriching wellness, mental health
Our friends at MD Anderson have published the results from their prospective study validating a new, user-friendly method in determining if genetic testing should be pursued, referred to as LFSPRO. Developed to assist genetic counselors, LFSPRO is a statistical tool that analyzes a patient's full family history to estimate the likelihood of a TP53 mutation.
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