September is Ovarian Cancer Awareness Month! Although not originally recognized as a common “core” cancer in Li-Fraumeni syndrome (LFS), ovarian cancers were documented (1) as subsequent tumors in patients with Li-Fraumeni syndrome as early as 1988. And though still considered “rare” in LFS, reproductive cancers are highlighted in research. In an August 2026 study by
Medulloblastoms are known to be associated with Li-Fraumeni syndrome. NIH National Library of Medicine: While leukemias are the most common type of malignancy affecting the pediatric population, brain tumors are the most common solid tumors in this population. Medulloblastoma is the most common malignant brain tumor in children, constituting nearly 20 percent of all pediatric
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