LFS: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations
Published August 2026, Li-Fraumeni Syndrome: Current Perspectives, is a comprehensive review on previously published work regarding molecular pathogenesis, international surveillance strategies, clinical
Lesko-Fleming Empowerment Grant for LFS Youth – Now accepting applications!
The Li-Fraumeni Syndrome Association (LFSA) is pleased to announce that applications are now open for the first annual Lesko-Fleming Empowerment Grant
Joseph Fraumeni, 93, Dies; Helped Discover Genetic Link to Cancer – The New York Times
July 13, 2026 print edition The New York Times July 9, 2026 By Trip Gabriel Considered the founder of
Clinical Characteristics and Cancer Histories Among Breast Cancer Patients With Li-Fraumeni Syndrome From a Single Institution
Diagnosing Li-Fraumeni syndrome soon after a patient's first cancer can reduce their overall cancer burden with an improved, personalized plan.
Collaboration or Partnership?
I had the opportunity to attend two conferences last month. The first brought me to Lugano, Switzerland, for the ESMO
Key Points for Individuals with a Variant of Uncertain Significance (VUS) in the TP53 Gene
Genetic testing is not always a one and done process: the classification of a variant may change over time, technologies
Lesko-Fleming Empowerment Grants
Through the tremendous generosity of the Lesko and Fleming families, a newly established annual grant program will provide support
LFS: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations
Published August 2026, Li-Fraumeni Syndrome: Current Perspectives, is a comprehensive review on previously published work regarding molecular pathogenesis, international surveillance strategies, clinical management, and
LFS: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations
Published August 2026, Li-Fraumeni Syndrome: Current Perspectives, is a comprehensive review on previously published work regarding molecular pathogenesis,
Lesko-Fleming Empowerment Grant for LFS Youth – Now accepting applications!
The Li-Fraumeni Syndrome Association (LFSA) is pleased to announce that applications are now open for the first
Joseph Fraumeni, 93, Dies; Helped Discover Genetic Link to Cancer – The New York Times
July 13, 2026 print edition The New York Times July 9, 2026 By Trip Gabriel
Novel tool more accurately predicts risk of Li-Fraumeni Syndrome
Our friends at MD Anderson have published the results from their prospective study validating a new, user-friendly method in determining if genetic testing should be
Li-Fraumeni Syndrome Family Education Day at Children’s National
Families of children with Li-Fraumeni syndrome are invited to join a dedicated day of education, connection, and support at Children’s National Hospital. This Family Education
Katherine M. Howley Endowment Fund for LFS Research
The Li-Fraumeni Syndrome Association (LFSA) is honored to announce the establishment of the Katherine M. Howley Endowment Fund for Li-Fraumeni Syndrome Research. This generous
LFSA at the SU2C Summit: Progress Through Partnership
As I reflect on my recent trip to California to attend the Stand Up To Cancer Scientific (SU2C) Summit, it is a frigid 2°F
Lakita Frida – the Face of Resilience
Lakita Frida was an energetic dynamo when she attended her first LFSA Youth Workshop in New York City back in 2023. This young Kenyan continues
Radiotherapy in Li-Fraumeni Syndrome: From Biological Concern to Personalized Clinical Decision-Making
The use of radiation is a challenge for Li-Fraumeni syndrome patients in regard to the increased risk of developing secondary, radiation-induced cancers. However, advances in















