LFSA China Chapter Hosts Its First Family Meeting
A milestone gathering brought together 46 members of the Li‑Fraumeni syndrome community in China to share knowledge, experiences, and hope. On October
Radiation and Li-Fraumeni Syndrome
NEW: Radiation Exposure and Li-Fraumeni Syndrome Everyone is exposed to ionizing radiation, an invisible form of high-energy radiation, in everyday life.
Ovarian cancers have been documented in LFS patients as early as the 1980s
September is Ovarian Cancer Awareness Month! Although not originally recognized as a common “core” cancer in Li-Fraumeni syndrome (LFS), ovarian cancers
LFS: Current Perspectives on Molecular Pathogenesis, Surveillance Strategies, Clinical Management and Pediatric Considerations
Published August 2026, Li-Fraumeni Syndrome: Current Perspectives, is a comprehensive review on previously published work regarding molecular pathogenesis, international surveillance
Lesko-Fleming Empowerment Grant for LFS Youth – Now accepting applications!
The Li-Fraumeni Syndrome Association (LFSA) is pleased to announce that applications are now open for the first annual Lesko-Fleming
Joseph Fraumeni, 93, Dies; Helped Discover Genetic Link to Cancer – The New York Times
July 13, 2026 print edition The New York Times July 9, 2026 By Trip Gabriel Considered the
Clinical Characteristics and Cancer Histories Among Breast Cancer Patients With Li-Fraumeni Syndrome From a Single Institution
Diagnosing Li-Fraumeni syndrome soon after a patient's first cancer can reduce their overall cancer burden with an improved, personalized plan.
LFSA China Chapter Hosts Its First Family Meeting
A milestone gathering brought together 46 members of the Li‑Fraumeni syndrome community in China to share knowledge, experiences, and hope. On October 25, 2026,
LFSA China Chapter Hosts Its First Family Meeting
A milestone gathering brought together 46 members of the Li‑Fraumeni syndrome community in China to share knowledge, experiences,
Radiation and Li-Fraumeni Syndrome
NEW: Radiation Exposure and Li-Fraumeni Syndrome Everyone is exposed to ionizing radiation, an invisible form of high-energy
Ovarian cancers have been documented in LFS patients as early as the 1980s
September is Ovarian Cancer Awareness Month! Although not originally recognized as a common “core” cancer in Li-Fraumeni
Collaboration or Partnership?
I had the opportunity to attend two conferences last month. The first brought me to Lugano, Switzerland, for the ESMO Sarcoma & Rare Cancers Annual
Key Points for Individuals with a Variant of Uncertain Significance (VUS) in the TP53 Gene
Genetic testing is not always a one and done process: the classification of a variant may change over time, technologies improve and better testing may
Lesko-Fleming Empowerment Grants
Through the tremendous generosity of the Lesko and Fleming families, a newly established annual grant program will provide support for two youth personally impacted
Novel tool more accurately predicts risk of Li-Fraumeni Syndrome
Our friends at MD Anderson have published the results from their prospective study validating a new, user-friendly method in determining if genetic testing should be
Li-Fraumeni Syndrome Family Education Day at Children’s National
Families of children with Li-Fraumeni syndrome are invited to join a dedicated day of education, connection, and support at Children’s National Hospital. This Family Education
Katherine M. Howley Endowment Fund for LFS Research
The Li-Fraumeni Syndrome Association (LFSA) is honored to announce the establishment of the Katherine M. Howley Endowment Fund for Li-Fraumeni Syndrome Research. This generous
